Neuroendocrine differentiated breast carcinoma: imaging features correlated with clinical and histopathological findings |
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Authors: | Günhan-Bilgen Isil Zekioglu Osman Ustün Esin Emin Memis Aysenur Erhan Yildiz |
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Institution: | (1) Department of Radiology, Ege University Hospital, Bornova, 35100 Izmir, Turkey,;(2) Department of Pathology, Ege University Hospital, Bornova, 35100 Izmir, Turkey, |
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Abstract: | The aim of this study was to describe the imaging features of neuroendocrine differentiated breast carcinoma (NEDBC) and
to correlate the radiological findings with the clinical and histopathological findings. A retrospective review of the mammograms
of 1845 histopathologically proven breast cancer cases revealed five NEDBC. The clinical, imaging, and histopathological findings
were analyzed. On mammography, a high-density mass was seen in all patients. The shape of the mass was round in 4 and irregular
in 1 patient. The margins were spiculated in 2, indistinct in 1, microlobulated in 1, and partially obscured in 1 patient.
On sonography, 4 patients had homogeneously hypoechoic masses with normal sound transmission. In 1 patient the mass was heterogeneously
hypoechoic with mild posterior acoustic enhancement. The margins were microlobulated in 2, irregular in 2, and well-circumscribed
in 1 patient. Neuroendocrine differentiated breast carcinoma should be included in the differential diagnosis of mammographically
dense, round masses with predominantly spiculated or lobulated margins. Sonographically, they mostly present as irregular
or microlobulated, homogeneously hypoechoic masses with normal sound transmission.
Electronic Publication |
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Keywords: | Breast Neuroendocrine differentiated breast carcinoma Mammography Sonography |
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