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锡类散预防酸性灌肠液致兔肠黏膜损伤的实验研究
引用本文:沈美云,张凤,徐旭娟,章建国,吴倩.锡类散预防酸性灌肠液致兔肠黏膜损伤的实验研究[J].护理学杂志,2011,0(18):1-3.
作者姓名:沈美云  张凤  徐旭娟  章建国  吴倩
作者单位:1. 南通大学附属医院妇产科(江苏南通,226001)
2. 南通大学护理学院(江苏南通,226001)
基金项目:南通市2008年指令性社会发展科技计划项目(S2008037)
摘    要:目的观察锡类散预防酸性灌肠液灌肠所致兔肠黏膜损伤的效果。方法将40只家兔随机分成两组各20只,对照组采用食醋灌肠,观察组采用食醋加锡类散灌肠。观测两组灌肠前后血钾水平变化及粪便涂片肠黏膜细胞脱落情况;将动物腹腔麻醉下取直肠、结肠肠壁制作病理切片,透射电镜观察肠黏膜细胞亚显微结构变化,光镜观察肠黏膜充血、水肿情况。结果对照组灌肠后血钾下降水平较观察组更为显著(P<0.01);病理切片及粪便涂片显示,对照组肠黏膜损伤及肠黏膜细胞脱落情况较观察组严重。结论锡类散可降低酸性灌肠液对兔肠黏膜损伤程度,具有一定的保护作用。

关 键 词:家兔  灌肠  酸性灌肠液  锡类散  肠黏膜损伤  食醋

Preventive effect of traditional Xilei powder on intestinal mucosal injury caused by acetic acid enema in rabbits
Shen Meiyun,Zhang Feng,Xu Xujuan,Zhang Jianguo,Wu Qian.Preventive effect of traditional Xilei powder on intestinal mucosal injury caused by acetic acid enema in rabbits[J].Journal of Nursing Science,2011,0(18):1-3.
Authors:Shen Meiyun  Zhang Feng  Xu Xujuan  Zhang Jianguo  Wu Qian
Institution:Shen Meiyun,Zhang Feng,Xu Xujuan,Zhang Jianguo,Wu Qian(Department of Gynecology and Obstetrics,Affiliated Hospital of Nantong University,Nantong 226001,China)
Abstract:Objective To explore the preventive effect of traditional Xilei powder on intestinal mucosal injury caused by acetic acid enema in rabbits.Methods Forty rabbits were randomized into 2 groups of 20.The control group received acetic acid enema,while the observation group were given enema solution containing vinegar and Xilei powder.Serum potassium was detected before and after enema,and exfoliative cells were observed in the stool smear.Then,pathological sections of the rectum and colon were obtained when the...
Keywords:rabbit  enema  acetic acid enema  Xilei powder  injuries of intestinal mucosa  vinegar  
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