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Ornithine phenylacetate targets alterations in the expression and activity of glutamine synthase and glutaminase to reduce ammonia levels in bile duct ligated rats |
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| Authors: | M. Jover-Cobos L. Noiret K. Lee V. Sharma A. Habtesion M. Romero-Gomez N. Davies R. Jalan |
| Affiliation: | 1 Liver Failure Group, UCL Institute for Liver and Digestive Health, Royal Free Hospital Campus, University College of London (UCL), Pond Street, London, United Kingdom;2 COMPLEX CoMPLEX, UCL, Gower Street, London WC1E 6BT, United Kingdom;3 Royal Veterinary College, Hatfield, Hertfordshire AL9 7TA, United Kingdom;4 CIBEREHD, UCM Digestive Diseases, Valme University Hospital, Seville, Spain |
| Abstract: | |
| Keywords: | HE, Hepatic encephalopathy ALF, Acute liver failure CLF, Chronic liver failure Gln, Glutamine Glu, Glutamate GS, Glutamine synthetase OP, Ornithinephenylacetate GA, Phosphate-activated glutaminase BDL, bile duct ligation O, Ornithine P, Phenylacetate PAGN, phenylacetylglutamine (PAGN) |
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