Reduced FOXP3 regulatory T cells in patients with primary sclerosing cholangitis are associated with IL2RA gene polymorphisms |
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Authors: | Marcial Sebode,Moritz Peiseler,Bjö rn Franke,Dorothee Schwinge,Tanja Schoknecht,Frederike Wortmann,Alexander Quaas,Britt-Sabina Petersen,Eva Ellinghaus,Udo Baron,Sven Olek,Christiane Wiegard,Christina Weiler-Normann,Ansgar W. Lohse,Johannes Herkel,Christoph Schramm |
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Affiliation: | 1 I. Department of Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany;2 Department of Pathology, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany;3 Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany;4 Epiontis GmbH, Berlin, Germany |
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Abstract: | |
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Keywords: | PSC, primary sclerosing cholangitis PBC, primary biliary cirrhosis Treg, regulatory T cells TSDR, Treg-specific demethylated region IL-2RA, Interleukin-2 receptor alpha |
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