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Hyper-IL-15 suppresses metastatic and autochthonous liver cancer by promoting tumour-specific CD8 T cell responses |
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| Authors: | Liang Cheng Xuexiang Du Zheng Wang Jianqi Ju Mingming Jia Qibin Huang Qiao Xing Meng Xu Yi Tan Mingyue Liu Peishuang Du Lishan Su Shengdian Wang |
| Institution: | 1 Key Laboratory of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China;2 University of Chinese Academy of Sciences, Beijing, China;3 Lineberger Comprehensive Cancer Center, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA |
| Abstract: | |
| Keywords: | IL-15 interleukin-15 IFN-γ interferon-γ HCC hepatocellular carcinoma DEN diethylnitrosamine NK cells natural killer cells NKT cells natural killer T cells CFSE carboxyfluorescein succinimidyl ester IHLs intrahepatic lymphocytes PBMC peripheral blood mononuclear cell |
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