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Warm vs. cold perfusion techniques to rescue rodent liver grafts
Authors:Andrea Schlegel  Philipp KronRolf Graf  Philipp Dutkowski  Pierre-Alain Clavien
Institution:Department of Surgery, University Hospital Zurich, Swiss HPB and Transplant Center, Zurich, Switzerland
Abstract:
Keywords:DCD  donation after cardiac death  HOPE  hypothermic oxygenated perfusion  UW solution  University of Wisconsin solution  HMGB-1  high mobility group box-1 protein  8-OHdG  8-hydroxy-2-deoxy guanosine  H&  E  haematoxylin and eosin  ROS  reactive oxygen species  DAMPs  damage associated molecular pattern signalling  CD68  macrosialin  ELISA  enzyme-linked immunosorbent assay  SECs  sinusoidal endothelial cells  WI  warm ischemia  IPRL  isolated perfused rat liver  TLR-4  Toll-like receptor 4  MPO  myeloperoxidase  IL-6  interleukin 6  IL-10  interleukin 10  IL-1β  interleukin 1β  TNF-α  tumor necrosis factor alpha  ICAM-1  intercellular adhesion molecule-1  NSE  neuron specific enolase  CXCL-5 (ENA-78)  epithelial neutrophil-activating protein 78
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