Effect of bariatric surgery on liver glucose metabolism in morbidly obese diabetic and non-diabetic patients |
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Authors: | Heidi Immonen,Jarna C. Hannukainen,Patricia Iozzo,Minna Soinio,Paulina Salminen,Virva Saunavaara,Ronald Borra,Riitta Parkkola,Andrea Mari,Terho Lehtimä ki,Tam Pham,Jukka Laine,Vesa Kä rjä ,Jussi Pihlajamä ki,Lassi Nelimarkka,Pirjo Nuutila |
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Affiliation: | 1 Turku PET Centre, Turku, Finland;2 Department of Medicine, Turku University Hospital, Turku, Finland;3 Institute of Clinical Physiology, National Research Council, Pisa, Italy;4 Department of Surgery, Turku University Hospital, Turku, Finland;5 Department of Radiology, Turku University Hospital, Turku, Finland;6 Institute of Biomedical Engineering, Padua, Italy;7 Department of Clinical Chemistry, Finlab Laboratories, Tampere University Hospital and University of Tampere School of Medicine, Finland;8 Department of Pathology, Turku University Hospital, Turku, Finland;9 Department of Pathology, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland;10 Department of Clinical Nutrition and Obesity Center, Kuopio University Hospital, Kuopio, Finland |
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Abstract: | |
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Keywords: | BS, bariatric surgery T2DM, type 2 diabetes EGP, endogenous glucose production HGU, hepatic glucose uptake VLCD, very-low-calorie diet PET, positron emission tomography 18F-FDG, 18F-fluorodeoxyglucose MRI, magnetic resonance imaging SG, sleeve gastrectomy RYGB, Roux-en-Y gastric bypass OGTT, oral glucose tolerance test MRS, magnetic resonance spectroscopy LFC, liver fat content HbA1c, glycosylated haemoglobin hs-CRP, high-sensitivity C-reactive protein IL-6, interleukin-6 IL-8, interleukin-8 MCP-1, monocyte chemotactic protein-1 GLP-1, glucagon-like peptide-1 |
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