| 清瘟解毒分散片质量标准研究 |
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| 引用本文： | 王晓莉,刘成松. 清瘟解毒分散片质量标准研究[J]. 中国中医药信息杂志, 2012, 19(1): 60-62 |
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| 作者姓名： | 王晓莉 刘成松 |
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| 作者单位： | 甘肃中医学院附属医院,甘肃兰州,730020 |
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| 摘 要： | 目的 建立清瘟解毒分散片的质量标准.方法 采用薄层色谱法对处方中的玄参、牛蒡子、葛根进行定性鉴别,采用高效液相色谱法测定黄芩中黄芩苷的含量.色谱柱填充剂:十八烷基硅烷键合硅胶；流动相:甲醇-水-磷酸(47∶53∶0.2)；检测波长:280 nm;流速:1.0 mL/min;柱温:25℃.结果 定性鉴别专属性强,黄芩苷进样量在0.104 ～0.520 μg范围内与峰面积积分值呈良好的线性关系(r=0.999 8),平均加样回收率为98.72％,RSD=1.31％(n=5).结论 所建立的标准可用于清瘟解毒分散片的质量控制.
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| 关 键 词： | 清瘟解毒分散片 黄芩苷 薄层色谱法 高效液相色谱法 质量标准 |
Quality Standard of Qingwen Jiedu Dispersible Tablets |
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| WANG Xiao-li , LIU Cheng-song. Quality Standard of Qingwen Jiedu Dispersible Tablets[J]. Chinese Journal of Information on Traditional Chinese Medicine, 2012, 19(1): 60-62 |
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| Authors: | WANG Xiao-li LIU Cheng-song |
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| Affiliation: | (The Affiliated Hospital of Gansu College of TCM, Lanzhou 730020, China) |
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| Abstract: | Objective To establish the quality standard of Qingwen Jiedu Dispersible Tablets. Methods Radix scrophulariae, Fructus arctill and Radix puerariae in the formulation were identified by TLC. The content of baicalin was determined by HPLC with C18 column and using a mobile phase of MeOH-water-phosphonic acid （47∶53∶0.2） under the flow rate of 1.0 mL/min. The column temperature was 25 ℃ and the detection wavelength was 280 nm. Results The quanitative identification was specific. The linear range of the baicalin was 0.104-0.520 ？g （r=0.999 8） and the average recovery rate was 98.72% （RSD=1.31%, n=5）. Conclusion The eatablished standard is suitable for the quality control of Qingwen Jiedu Dispersible Tablets. |
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| Keywords: | Qingwen Jiedu Dispersible Tablets baicalin TLC HPLC quality standard |
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