Effect of nitroglycerin on regulation of the cerebral circulation

Investigations by the use of radioisotopes and electromagnetic and resistographic methods showed that nitroglycerine increases the cerebral blood flow and lowers the tone of the intracranial vessels. It also has a marked depriming effect on the central regulation of the cerebral circulation, inhibits cerebrovascular reflexes, and has a protective effect in experimental disturbances of the cerebral circulation of adrenergic nature.Laboratory of Pharmacology of the Nervous System, Institute of Pharmacology, Academy of Medical Sciences of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR V. V. Zakusov.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 82, No. 9, pp. 1081–1083, September, 1976.