H+/amino acid transporter 1 (PAT1) is the imino acid carrier: An intestinal nutrient/drug transporter in human and rat期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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H+/amino acid transporter 1 (PAT1) is the imino acid carrier: An intestinal nutrient/drug transporter in human and rat

Authors:	Anderson Catriona M H Grenade Danielle S Boll Michael Foltz Martin Wake Katherine A Kennedy David J Munck Lars K Miyauchi Seiji Taylor Peter M Campbell Frederick Charles Munck Bjarne G Daniel Hannelore Ganapathy Vadivel Thwaites David T

Institution:	Faculty of Medical Sciences, nUniversity of Newcastle Upon Tyne, Newcasttle Upon Tyne, UK.

Abstract:

Keywords:	ABA aminobutyric acid BCECF 2′ 7′-bis(2-carboxyethyl)-5(6)-carboxyfluorescein BBMV brush-border membrane vesicles bp base pair cAMP 3′ 5′-cyclic monosphosphate EIPA N-(ethyl-N-isopropyl)-amiloride GABA γ-aminobutyric acid hPAT1 human proton-coupled amino acid transporter 1 hPepT1 human intestinal di/tripeptide transporter HRPE human retinal pigment epithelial Ki inhibition constant K_m Michaelis constant LYAAT1 lysosomal amino acid transporter-1 MeAIB methylaminoisobutyric acid MeLeu methyl-leucine mPAT1 mouse proton-coupled amino acid transporter 1 NHE Na⁺/H⁺ exchanger PAT proton-coupled amino acid transporter PCR polymerase chain reaction PepT1 di/tripeptide transporter pH_i intracellular pH rBAT related to b⁰ + amino acid transporter VIP vasoactive intestinal polypeptide
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