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Meta分析中的异质性检验方法
引用本文:何寒青,陈坤. Meta分析中的异质性检验方法[J]. 中国卫生统计, 2006, 23(6): 486-487,490
作者姓名:何寒青  陈坤
作者单位:浙江大学医学院流行病学与卫生统计学教研室,310031
摘    要:目的比较和探讨meta分析中异质性定量化的检验方法。方法通过比较Q检验以及H和I^2统计量等方法,结合一个实例进行分析,来研究meta分析中异质性的定量化检验方法。结果Q检验容易受到样本量变化的影响,而H和I^2统计量经过对自由度的校正,不会受到文献数目变化的影响,异质性结果检验较为稳健。结论H和I^2统计量计算简单,检验结果也稳定可靠,是meta分析中异质性检验和异质性来源研究中值得推广应用的方法。

关 键 词:Meta分析  异质性  统计学检验

Methods for Measuring Heterogeneity in a Meta - analysis
He Hanqing,Chen Kun. Methods for Measuring Heterogeneity in a Meta - analysis[J]. Chinese Journal of Health Statistics, 2006, 23(6): 486-487,490
Authors:He Hanqing  Chen Kun
Affiliation:Department of Epidemic and Health Statistics , School of Medicine, Zhejiang University (310031
Abstract:Objective To demonstrate the optimal methods of heterogeneity test in meta- analysis. Methods Q - test, H and 12 statistics were compared to test the existence of heterogeneity in meta - analysis in this study. Results In these methods, Q - test was poor in detecting the true heterogeneity among studies when meta - analysis includes small numbers of studies, while H and 12 statistics were independent of the num-her of studies in meta - analysis. Conclusion We propose H and 12 staffsties as the methods for testing heterogeneity in the meta - analysis, and both of them can be readily calculated.
Keywords:Meta - analysis   Heterogeneity   Statistical test
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