Radioprotective action of lymphokinin,a composite preparation of cytokines

Lymphokinin injected into mice in a dose of 25,000 U/kg intraperitoneally before or after their single irradiation producing acute radiation sickness is found to prolong their survival. The optimal time for administering Lymphokinin depends on the radiation dose. Its survival-prolonging effect is most marked when it is injected 1 h or 24 h before or 23 h after exposure to a dose of 6.0 Gy. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 118, N ^o 7, pp. 38–40, July, 1994 Presented by N. N. Trapeznikov, Member of the Russian Academy of Medical Sciences