肺部医院获得性丝状真菌感染及其相关危险因素分析

目的了解肺部丝状真菌感染特点并调查其相关危险因素。方法采用回顾性调查方法对某医院过去5年临床肺部医院获得性丝状真菌感染的临床资料进行统计分析。结果1138例肺部感染病例中发生肺部医院获得性丝状真菌感染36例（3．16％），感染菌种以曲霉菌为主，包括烟曲霉菌、黄曲霉菌、黑曲霉菌、土曲霉菌等。感染的危险因素有年龄、住院时间、抗生素、呼吸机、皮质粪田醇激素、侵入性诊疗措施等。感染病例的死亡率明显高于非感染病例，预后差。结论肺部医院获得性丝状真菌感染率高，危险因素多，应采取综合措施将其预防和控制。

Investigation of nosocomially acquired mycelial fungus infection in lung and its risk factors analysis

Objective To grasp the features of nosocomially acquired mycelial fungus infection and to investigate its risk factors. Methods The clinical data of all patients hospitalized in the past five years were surveyed retrospectively.Results Thirty-six cases were diagnosed nosocomially acquired mycelial fungus infection from 1138 cases.The positive rate was 3.16 percent.The main pathogens were aspergillus such as aspergillus fumigatus,flavus,black aspergillus,clay aspergillus,etc.The risk factors of noso- comial infection included age,length of hospital stay,antibiotics,breathing machine,cortieosteroid hormone,invasive diagnostic and treat measures,etc.The cause fatality rate of infected patients was significantly higher than that of non-infected patients' and the prognosis was bad.Conclusion The positive rate of nosocomially acquired mycelial fungus infection in lung is high and there are many important risk factors.Comprehensive measures should be taken to control nosocomial infection.