| S-腺苷蛋氨酸联合护理干预治疗慢性丙型肝炎伴抑郁症的临床观察 |
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| 引用本文： | 杨文英,李莉. S-腺苷蛋氨酸联合护理干预治疗慢性丙型肝炎伴抑郁症的临床观察[J]. 现代保健, 2012, 0(4): 14-15 |
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| 作者姓名： | 杨文英 李莉 |
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| 作者单位： | 新疆医科大学第一附属医院,830054 |
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| 基金项目： | 国家自然科学基金资助项目（编号：30760220） |
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| 摘 要： | 目的探讨S-腺苷蛋氨酸联合护理干预对慢性丙型肝炎伴抑郁症患者抗抑郁治疗的效果。方法接受Peg-IFN-2a治疗的慢性丙型肝炎患者10例，在治疗期间发生抑郁症后给予s-臁苷蛋氨酸500mg／d口服治疗，同时对患者实施护理干预，治疗4周和8周评定ZDS积分。结果治疗4周、8周后，ZDS积分分别为（45．5±4．4）、（37．8±6．0），两者差异有统计学意义（P〈O．05）。结论S-腺苷蛋氨酸结合有效护理干预能快速有效的治疗慢性丙型肝炎伴抑郁症。
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| 关 键 词： | 慢性丙型肝炎 干扰素 抑郁症 S-腺苷蛋氨酸 护理干预 |
Clinical observation of SAMe combine with nursing intervention in treatment of Chronic hepatitis C with depression |
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| YANG Wen -ying,LI Li. Clinical observation of SAMe combine with nursing intervention in treatment of Chronic hepatitis C with depression[J]. , 2012, 0(4): 14-15 |
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| Authors: | YANG Wen -ying LI Li |
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| Affiliation: | . The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China |
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| Abstract: | Objective To explore the efficacy of SAMe combine with nursing intervention in treatment of chronic hepatitis C with depression. Methods 10 patients of chronic hepatitis C treated with Peg - IFN - 2a accepted SAMe oral medication and nursing intervention when depression occurred. To evaluate the grades of ZDS after 4 weeks and 8 weeks. Results 4,8 weeks later, the score of ZDS was （45.5 ~ 4.4 ）, （37.8 ~ 6.0 ） respectively, there was significant difference between them. Conclusion SAMe combine with nursing inter- vention is an effective way for the treatment of IFN associated depression. |
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| Keywords: | Chronic hepatitis C IFN Depression SAMe Nursing intervention doi：10. 3969/j. issn. 1674 -4985. 2012.04. 006 |
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