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抗药性与敏感性德国小蠊乙酰胆碱酶的活性比较
引用本文:王式春,林琳,刘渠,张起文,沈培林,韦薇,王德全.抗药性与敏感性德国小蠊乙酰胆碱酶的活性比较[J].广东寄生虫学会年报,2011(7):748-749.
作者姓名:王式春  林琳  刘渠  张起文  沈培林  韦薇  王德全
作者单位:[1]深圳市龙岗区疾病预防控制中心,广东深圳518172 [2]广东药学院,广东广州510046
摘    要:目的研究德国小蠊抗药性与乙酰胆碱酯酶活性的关系。方法采用化学比色方法对敏感品系和抗性品系的德国小蠊分别测试乙酰胆碱酯酶,对比两者的测定值,分析抗性品系和敏感品系德国小蠊乙酰胆碱酯酶的差异。结果敏感品系和抗性品系德国小蠊的乙酰胆碱酯酶活性分别是2.863和5.609,抗性品系德国小蠊酶活性显著高于敏感品系,两者酶活性比值为1.96。结论乙酰胆碱酯酶活性与德国小蠊抗药性有关。

关 键 词:德国小蠊  乙酰胆碱酯酶  抗性

A comparative study on the activity of acetylcholinesterase in the pesticides resistant strains of Blattella germanica
WANG Shi-chun,LIN Lin,LIU Qu,ZHANG Qi-wen,SHEN Pei-lin,WEI wei,WANG De-quan.A comparative study on the activity of acetylcholinesterase in the pesticides resistant strains of Blattella germanica[J].Journal of Tropical Medicine,2011(7):748-749.
Authors:WANG Shi-chun  LIN Lin  LIU Qu  ZHANG Qi-wen  SHEN Pei-lin  WEI wei  WANG De-quan
Institution:1.Shenzhen Longgang Center for Disease Control and Prevention,Shenzhen 518172;2.Guangdong Pharmaceutical University,Guangzhou 510046,China)
Abstract:Objective To study the activity of acetylcholinesterase(AChE) in insecticide resistant German cockroaches.Methods Different strains and gender of German cockroaches were used in this study.Colorimetric method was used to determine the activity of acetylcholinesterase.Results Blattella germanica were studied for their acetylcholinesterase activity.AChE activity in the insecticide resistant and insecticide sensitive strains was 2.863 and 5.609,respectively.AChE activity of the field strain was significantly higher than the susceptible strain.And the ratio of AChE activity between the resistant and the sensitive strain was 1.96.Conclusion The activity of AChE from the field strains was correlated with the pesticides resistance.
Keywords:Blattella germanica  acetylcholinesterase  pesticides resistance
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