| 炒牛蒡子配方颗粒HPLC指纹图谱研究 |
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| 引用本文： | 狄恒建,李 松,郭 青,胡浩斌,周嘉琳,徐以亮.炒牛蒡子配方颗粒HPLC指纹图谱研究[J].药学与临床研究,2013,21(6):637-639. |
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| 作者姓名： | 狄恒建 李 松 郭 青 胡浩斌 周嘉琳 徐以亮 |
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| 作者单位： | 江苏省食品药品检验所;江阴天江药业有限公司 |
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| 基金项目： | 国家药典委员会课题-炒牛蒡子配方颗粒质量标准示范性研究 |
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| 摘 要： | 采用RP-HPLC指纹图谱技术,对炒牛蒡子配方颗粒进行指纹图谱研究,并建立共有模式,同时,采用"中药色谱指纹图谱相似度评价系统"对所得图谱进行相似度评价。结果表明:10批炒牛蒡子配方颗粒的指纹图谱共有峰均有18个,各组分可很好的分离,相似度评价均大于0.90;其指纹图谱之间无明显差异,品质基本一致,为今后炒牛蒡子配方颗粒的质量标准研究和品质鉴定提供了科学依据。
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| 关 键 词： | 炒牛蒡子 配方颗粒 RP-HPLC 指纹图谱 |
| 收稿时间： | 2013/8/19 0:00:00 |
| 修稿时间： | 2013/9/17 0:00:00 |
HPLC Fingerprint of the Dispensing Granule of Parched Fruit of Arctium lappa |
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| DI Heng-jian,LI Song,GUO Qing,HU Hao-bin,ZHOU Jia-lin and XU Yi-liang.HPLC Fingerprint of the Dispensing Granule of Parched Fruit of Arctium lappa[J].Pharmacertical and Clinical Research,2013,21(6):637-639. |
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| Authors: | DI Heng-jian LI Song GUO Qing HU Hao-bin ZHOU Jia-lin and XU Yi-liang |
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| Institution: | DI Heng-jian;LI Song;GUO Qing;HU Hao-bin;ZHOU Jia-lin;XU Yi-liang;Jiangsu Institute for Food and Drug Control;Jiangyin Tianjiang Pharmaceutical Limited Company; |
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| Abstract: | The fingerprint of the dispensing granule of parched fruit of Arctium lappa (DGPFAL) was studied by HPLC, the common pattern of DGPFAL was established at the same time, and their similarities were evaluated by the Similarity Evaluation System for Chromatographic Fingerprint of TCM. Results: There were 18 common characteristic peaks in the fingerprint of DGPFAL they were all being separated effectively, the similarities among them were all more than 0.90. There were no obvious difference between different batches of samples, the quality of them were basically identical. The study can provide some scientific basis for quality control and identification of DGPFAL. |
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| Keywords: | Parched fruit of Arctium lappa Dispensing granule RP-HPLC Fingerprint |
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