CD8-positives,CD30-negatives kutanes T-Zell-Lymphom unter dem klinischen Bild eines Pyoderma gangraenosum |
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| Authors: | D Dueck B Hermes H Audring P K Kohl |
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| Institution: | 1.Abteilung für Dermatologie und Venerologie, Krankenhaus Neuk?lln, Berlin,DE;2.Hautklinik der Charité, Humboldt-Universit?t zu Berlin,DE |
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| Abstract: | Ulcerated primary cutaneous lymphomas are not rare, but the clinical manifestation as a pyoderma gangrenosum look-alike is extraordinary. CD8-positive lymphomas are rare, unclassifiable tumours with variable prognosis. We report on a 49-year-old patient with a large ulcerated primary cutaneous lymphoma on the left chest wall presenting as pyoderma gangrenosum. With immunohistochemical staining, most lymphocytes were shown to be CD8-positive. The CD30 antigen was not expressed. After radiotherapy with complete skin irradiation, the lymphoma regressed completely. The patient has been free of relapse for 28 months so far. |
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