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Pregnancy and heart disease: Time for a randomized controlled trial
Authors:Mark Johnson  Michael Gatzoulis  Jolien Roos-Hesselink
Affiliation:1. Academic Department of Obstetrics and Gynaecology, Faculty of Medicine, Imperial College London, Chelsea and Westminster NHS Foundation Trust, 369 Fulham Road, London SW10 9NH, UK;2. Adult Congenital Heart Disease Unit, Royal Brompton and Harefield NHS Foundation Trust, UK;3. The National Heart and Lung Institute at Imperial College, Sydney Street, London SW3 6NP, UK;4. Department of Cardiology, Erasmus University Medical Center, Rotterdam, The Netherlands
Abstract:Cardiac disease is the most important cause of maternal mortality and despite considerable efforts by cardiologists and obstetricians alike, the numbers of deaths continue to rise. The literature on the subject is limited and almost entirely made up of case series. In this editorial we consider the need for randomized controlled trials in key areas, some will be harder than others to complete, but all are required to help reverse the growing numbers of women who die from heart disease during pregnancy.
Keywords:Pregnancy   Heart disease   Anticoagulation   Prosthetic valve   Cardiomyopathy   Beta blockers
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