Redefining the ECG in urban South Africans: Electrocardiographic findings in heart disease-free Africans |
| |
Authors: | Karen Sliwa Geraldine A Lee Melinda J Carrington Pro Obel Andrzej Okreglicki Simon Stewart |
| |
Institution: | 1. Hatter Institute for Cardiovascular Research in Africa & IIDMM, Faculty of Health Sciences, University of Cape Town, South Africa;2. Soweto Cardiovascular Research Unit, Chris Hani Baragwanath Hospital, University of the Witwatersrand, Johannesburg, South Africa;3. Baker IDI Heart and Diabetes Institute, Melbourne, Australia;4. Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia;5. Milpark Hospital, Johannesburg, South Africa |
| |
Abstract: | BackgroundThe 12-lead electrocardiogram (ECG) represents an important diagnostic tool for detecting heart disease, but the “normal” ECG in those of African descent has yet to be definitively described.MethodsWe systematically analysed 12-lead ECGs from 387 urban South Africans determined to be heart disease free (using the Minnesota code) following advanced cardiologic assessment, including echocardiography, at the Baragwanath Hospital in Soweto, South Africa.Results123 males (32%, 41.2 ± 14.5 years) and 264 females (37.4 ± 14.2 years) were studied. Most were in sinus rhythm (87%) and had normal axis (89%). Mean interval data were: PR interval (156 ± 28 ms; 95% CI: 153–159 ms), QRS duration (82 ± 16 ms; 95% CI: 80–84 ms), QT interval (379 ± 48 ms; 95% CI: 374–384 ms) and QTc interval (426 ± 32 ms; 95% CI: 423–429 ms). Overall, 199 (51%; 95% CI: 46.0% to 56.0%) subjects had an ECG “abnormality” or normal variant and 67 ECGs (17%; 95% CI: 13.3% to 20.7%) had major and minor abnormalities. ECG changes normally ascribed to myocardial ischaemia were: i) ST elevation (9.3%; 95% CI: 6.2 to 11.9%), ii) Q waves (7.4%; 95% CI: 4.4 to 9.5%) and iii) ST depression (2.3%; 95% CI: 0.8 to 3.8%). Sokolow–Lyon Index voltage exceeding 38 mm indicative of left ventricular hypertrophy was more prominent in males than females (23.6% vs. 6.4%; OR = 4.5; 95% CI: 2.3–8.5).ConclusionsThese data provide a contemporary reference to the 12-lead ECG in urban South Africans found to be heart disease free, with both major and minor abnormalities detected. |
| |
Keywords: | Urban Africans 12-lead ECG Minnesota coding |
本文献已被 ScienceDirect 等数据库收录! |
|