| TRT在ED合并LOH患者中应用的研究进展 |
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| 引用本文： | 赵学军,冯亮. TRT在ED合并LOH患者中应用的研究进展[J]. 医疗保健器具, 2012, 19(1): 158-160. DOI: 10.3969/j.issn.1674-4659.2012.01.0158 |
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| 作者姓名： | 赵学军 冯亮 |
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| 作者单位： | 1. 南昌大学研究生院医学部2009级,江西南昌,330006
2. 南昌大学第一附属医院泌尿外科,江西南昌,330006 |
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| 摘 要： | 男性迟发性性腺功能减退症(LOH)是一种与年龄相关的、具有典型临床症状和血清睾酮水平低下的综合征,勃起功能障碍(ED)是LOH患者最常见症状之一.中老年男性ED的致病因素复杂,而睾酮缺乏是其中的重要因素.睾酮在阴茎勃起的生理生化方面起着重要的作用.睾酮替代治疗(TRT)联合磷酸二酯酶5型抑制剂能提高磷酸二酯酶5型抑制剂单一治疗ED合并LOH失败患者的性功能.
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| 关 键 词： | 勃起功能障碍 迟发性性腺功能减退症 睾酮 磷酸二酯酶5型抑制剂 睾酮替代治疗 |
Applications of TRT in Patients with ED and LOH |
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| ZHAO Xuejun,FENG Liang. Applications of TRT in Patients with ED and LOH[J]. Medicine Healthcare Apparatus, 2012, 19(1): 158-160. DOI: 10.3969/j.issn.1674-4659.2012.01.0158 |
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| Authors: | ZHAO Xuejun FENG Liang |
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| Affiliation: | 1Grade 2009 of Medical Department of Graduate School, Nanchang University, Nanchang 330006, China; 2Department of Urology, the First Affiliated Hospital, Nanchang University, Nanchang 330006, China) |
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| Abstract: | Male late-onset hypogonadism（LOH） is a clinical and biochemical syndrome which is age-associated with typically clinical symptoms and a deficiency in serum testosterone levels. Erectile dysfunction plays an important role in its pathogenesis. Testosterone deficiency is a significant factor which induces erectile dysfunction. Testosterone plays an important role in erectile biologic and psychological factors. Combination therapy with testosterone replacement therapy （TRT） and phosphodiestcrase type5 inhibitors can improve sexual function of patients with ED and LOH, who are unresponsive to phosphodiesterase type5 inhibitors alone. |
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| Keywords: | Erectile dysfunction Late-onset hypogonadism Testosterone Phosphodiesterase type5 inhibitor Testosterone replacement therapy |
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