3.0T磁共振弥散加权成像在胰腺癌中的应用价值

目的:分析评价在3.0T磁共振非脂肪抑制憋气DWl序列在胰腺癌中的应用价值.方法-30例正常志愿者与30例经手术病理证实的胰腺癌患者,在3.0T磁共振上,术前行基于SE-EPI的非脂肪抑制憋气DWI序列,b值为0和600s/mm2,统计学比较分析正常胰腺、胰腺癌及远端炎症区的ADC值.结果:不同组织的ADC值从低到高依次为胰腺癌、正常胰腺、远端炎症,单因素方差分析显示不同组织的ADC值有明显统计学差异,F值为18.716,P值为0.0004,两两比较分析显示胰腺癌分别与正常胰腺及远端炎症的ADC值统计学有明显差异,P值分别为0.00483及0.00191.结论:在3.0T磁共振上,非脂肪抑制憋气DWI序列有助于病灶筛查,其ADC值能够较好的反映胰腺癌、正常胰腺及远端炎症的组织病理状态.

The applied value of breath-holding diffusion-weighted MR imaging for pancreatic carcinoma at 3.0 T

Objective：The purpose of this study was to investigate the value of breath-holding diffusion-weighted MR imaging at 3.0 T in pancreatic carcinoma.Methods：30 normal volunteers and 30 patients with pancreatic cancer proven by histopathology underwent breath-holding diffusion-weighted MR imaging without fat suppression before operation,based on SE-EPI sequence and b values=0 and 600 s/mm2.ADC values were statistically investigated and compared among pancreatic cancer,normal pancreas,and distal pancreatitis.Results：The ADC value of pancreatic cancer was the lowest,then followed by normal pancreas and distal pancreatitis,and there were statistical differences among them by ANOVA（F=18.716,P=0.0004）;ADC value of pancreatic cancer was statistically lower than that of normal pancreas or distal pancreatitis（P=0.00483 and P=0.00191 respectively）.Conclusion：Breath-holding DWI at 3.0 T helps to detect the lesion,and its ADC value can better disclose histopathological state in pancreatic cancer,normal pancreas and distal pancreatitis.