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钙镁拮抗氟的胶原毒性实验研究
引用本文:陈国立 侯悦. 钙镁拮抗氟的胶原毒性实验研究[J]. 中华预防医学杂志, 1992, 26(2): 80-82
作者姓名:陈国立 侯悦
摘    要:

关 键 词:钙 镁 氟化物中毒 胶原

Experimental study of antagonizing effect of calcium and magnesium against fluoride toxicity in collagen]
G L Chen. Experimental study of antagonizing effect of calcium and magnesium against fluoride toxicity in collagen][J]. Chinese Journal of Preventive Medicine, 1992, 26(2): 80-82
Authors:G L Chen
Affiliation:Research Center for Prophylaxis and Treatment of Injuries in Train of PLA.
Abstract:SD rats were given fluoride 20 mg/kg for 14 days through a gastrointestinal tube, body weight growth depressed obviously, the ratio of the Liver and Kidney weight to body weight increased significantly, hemoglobin concentration dropped and morphology and metabolism of collagen all became abnormal. All these effects can be antagonised by giving calcium (100 mg/kg), magnesium (100 mg/kg) or calcium and magnesium combined (50 mg/kg each). When Ca and Mg is given combined, the antagonizing effect is even better.
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