Single chromosome defect, partial trisomy 1q, in a colon cancer cell line |
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| Authors: | D J Jenkyn R H Whitehead A K House M A Maley |
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| Affiliation: | 2. Laboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD;3. Department of Chemistry and Biochemistry and the Comprehensive Cancer Center, The Ohio State University, Columbus, OH;4. High Dimension Data Analysis Group, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD;5. Laboratory of Gastrointestinal and Pancreatic Oncology, Institut D''Investigacions Biomèdiques August Pi i Sunyer, Hospital Clínic of Barcelona, CIBERehd, Barcelona, Spain |
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| Abstract: | The characterization of a single chromosome defect previously reported in a case of inherited nonpolyposis colorectal cancer is the essence of this communication. The defect, originally described as 13p+, is now being defined and the karyotype designated as 46,XY,-13,+der(13)t(1;13)(q32.1;p11). |
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