原发性肝癌肝外动脉供血的临床意义及介入治疗

目的 :探讨肝癌的肝外动脉供血规律、插管技术及介入治疗。方法 :4 6例原发性肝癌患者发现肝外动脉供血5 1条 ,分别超选择插管行化疗栓塞。结果 :肝外动脉供血与肿瘤部位、大小密切相关。治疗三周后复查 ,肿瘤缩小 >5 0 %者 14例 (30 .4 % ) ;肿瘤缩小 <5 0 %而 >2 5 %者 2 2例 (47.8% ) ;肿瘤无明显变化 10例 (2 1.7% )。AFP下降 >5 0 %者 2 8例(80 .0 % )。肝功能损害轻 ,全部患者术后无严重并发症。结论 :肝癌有丰富的肝外动脉供血。对肝外动脉供血支超选择性栓塞治疗 ,对提高中晚期肝癌患者介入治疗疗效具有重要的临床意义

The clinical significance of extrahepatic arterial blood supply of primary hepatic carcinoma and interventional therapy

Objective:To study the pattern extrahepatic arteriy supply to primary hepatic carcinoma(PHC) and catheterization technique for intervertional therapy.Methods:58 collateral arterial pathways were found in 46 PHC patients.Super selective catherization and transcatheter arterial chemoembolization (TACE) to extrahepatic arteriy were performed respectively.Results:There was close correlation between extrahepatic arterial blood supply and location and size of tumor.Serum AFP reduced over 50% was noted in 28 patients(80 0%),while tumor size reduced over 50% in 12 cases (28.6%) and less than 50% in 22 cases (52.4%).Liver function damage after TACE was slight and no serious complication occurred in all patients.Conclusion:Ample extrahepatic arterial blood supply is found in PHC.TACE in superselective with extrahepatic arteriy supply of PHC patients has very important clinical significance ofr better efficacy.