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Restriction Fragments Length Polymorphism in the NAT1 Gene of Europeans in West Siberia
Authors:M V Nikishina  A G Akishev  V A Vavilin  S I Makarova  S Kh Degtyarev  V V Lyakhovich
Institution:Institute of Molecular Biology and Biophysics, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia.
Abstract:Restriction fragment length polymorphism in the NAT1 gene was assayed to reveal 7 mutations (97C>T; 190C>T; 350,351G>C; 402T>C; 752A>T; D(1105); D(1025)) in 74 Europeans from West Siberia. New methods for detecting mutations 350,351G>C, 402T>C, 752A>T, D(1105), and D(1025) were proposed.
Keywords:genetic polymorphism  NAT1  restriction endonucleases  polymerase chain reaction
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