秦皮挥发油成分的GC-MS分析 |
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引用本文: | 崔伟,;徐淑楠,;刘建华,;高玉琼,;王巧荣. 秦皮挥发油成分的GC-MS分析[J]. 中国药房, 2014, 0(35): 3310-3312 |
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作者姓名: | 崔伟, 徐淑楠, 刘建华, 高玉琼, 王巧荣 |
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作者单位: | [1]贵州省生物技术研究开发基地,贵阳550002; [2]山东威高药业股份有限公司研发中心,山东威海264209; [3]贵州大学生命科学学院,贵阳550025 |
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基金项目: | 贵州省科技计划课题(No.黔科合院所创能[2009]4010) |
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摘 要: | 目的:为秦皮药材的进一步研究和开发提供科学依据。方法:利用水蒸气蒸馏法提取秦皮挥发油,采用气相色谱-质谱(GC-MS)联用技术对挥发油成分进行分析鉴定,用峰面积归一化法计算各成分的质量分数。结果:共分离出65个化学成分,鉴别出61个化学成分,占挥发油总量的93.968%。其中,质量分数较大的成分有4-己基-2,5-二氧代呋喃-3-乙酸(10.197%)、3-氟-4-甲氧基苯胺(9.846%)、葡萄螺烷(7.252%)、1-十五烯(7.228%)、右旋橙花叔醇(6.501%)、氧化芳樟醇(5.465%)、α-红没药醇(4.959%)、反-氧化芳樟醇(4.582%)、4-萜烯醇(3.203%)、柠檬烯(2.134%)、正癸酸(2.019%)。结论:GC-MS联用技术可快速、准确地鉴别秦皮挥发油成分,为秦皮资源的综合开发利用提供了基础数据。
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关 键 词: | 秦皮 水蒸气蒸馏 气相色谱-质谱联用 挥发油 |
GC-MS Analysis of Volatile Oil from Cortex Fraxini |
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Affiliation: | CUI Wei ,XU Shu-nan,LIU Jian-hua, GAO Yu-qiong ,WANG Qiao-rong( 1.Guizhou Base of Biotechnology Research and Development, Guiyang 550002, China; 2.R&D Center, Shandong Weigao Pharmaceutical Co., Ltd., Shandong Weihai 264209, China;3.College of Life Science,Guizhou University, Guiyang 550025, China) |
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Abstract: | OBJECTIVE:To provide scientific evidence for further RD of Cortex Fraxini. METHODS:The volatile oil was extracted from Cortex Fraxini by steam distillation. The volatile oil was analyzed by GC-MS and the mass fraction of each component was calculated by normalization method. RESULTS:65 chemical compounds were separated and 61 of them were identified,which accounted for 93.97% of all the volatile oil. The major components were 4-hexyl-2,5-dioxo furan-3-acetic acid(10.197),3-fluoro-4-methoxyaniline(9.846),vitis-pirane(7.252),1-pentadecene(7.228%),D-nerolidol(6.501%),linalyl oxid(5.465%),α-bisabolo(4.959%),trans-linalool oxide(4.582%),4- terpenol(3.203%),limonene(2.134%)and n-decanoic acid(2.019%).CONCLUSIONS:The volatile oils of Cortex Fraxini can be accurately identified by GC-MS rapidly,which provide basic data for comprehensive utilization of Cortex Fraxini. |
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Keywords: | Cortex Fraxini Steam distillation GC-MS Volatile oil |
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