2家医院2012-2013年儿科呼吸系统疾病病原菌耐药性分析

目的:了解2家医院儿科呼吸系统疾病4种常见病原菌的耐药性,为临床经验治疗相关疾病选择抗菌药物提供依据。方法:收集2家医院2012-2013年儿科呼吸系统疾病住院患者3 957例资料,统计细菌培养结果,分析检出率较高的4种细菌药敏试验结果,比较2年内同一细菌的耐药性变化。结果:2家医院儿科呼吸系统疾病细菌培养检出率较高的是金黄色葡萄球菌、肺炎链球菌、大肠埃希菌和肺炎克雷伯菌。4种细菌在2年内耐药性有一定的变化,但变化不太大。结论:2家医院相关疾病的病原菌及其耐药性均呈现地区特异性,且耐药性有一定的年度变化。临床可根据本地区耐药谱经验用药,并结合药敏试验结果合理选择抗菌药物。

Analysis of Drug Resistance of Pathogenic Bacteria of Infection Respiratory System Disease in Pediatric De- partment of 2 Hospitals during 2012--2013

OBJECTIVE： To investigate the drug resistance of 4 common pathogens of respiratory system disease in pediatric de- partment of 2 hospitals, and to provide reference for related disease treatment and rational selection of antibiotics.METHODS： 3 957 medical records of inpatients with respiratory system diseases were collected from pediatric departments of 2 hospitals during 2012- 2013.The bacterial culture and drug sensitivity tests of 4 kinds of bacteria which had high detection rates were analyzed statistically, and drug resistance of bacterial were compared within 2 years.RESULTS： The bacteria in the list of high detection rate were Staphylo- coccus aureus, Streptococcus pneumoniae, Escherichia coli and Klebsiella pneumoniae.There were small differences in drug resistance of 4 kinds of bacterial within 2 years.CONCLUSIONS： The pathogenic bacteria and drug resistance of related diseases in 2 hospitals show regional specificity, and their drug resistance have changed with the change of year.The doctor can choose the drugs empirically according to drug resistant spectrum and select antibiotics reasonably based on drug sensitivity test for further treatment.