我院万古霉素药物利用评价

目的:为临床合理使用万古霉素提供参考依据。方法:抽取2013年1月1日-6月30日我院使用万古霉素的出院患者病历,参照国内万古霉素药物利用评价标准,并结合我院实际情况设计的患者使用万古霉素调查表,采用回顾性分析方法,评价万古霉素的使用情况。结果:我院万古霉素临床使用过程中,在患者治疗前后体温监测、白细胞计数、第1次使用48 h以内细菌培养等方面符合标准率均为100%;在用药指征、用法用量及用药疗程、药物相互作用等方面存在不合理现象,其中用药指征符合标准率为63.33%,用法用量及用药疗程符合标准率为51.67%,药物相互作用符合标准率为61.67%。结论:通过开展万古霉素药物利用评价,可发现临床用药过程中存在的问题或不足,有利于促进万古霉素的合理使用。

Drug Utilization Evaluation of Vancomycin in Our Hospital

OBJECTIVE：To provide reference for the reasonable use of vancomycin in our hospital. METHODS：According to the domestic drug utilization evaluation（DUE）criteria of vancomycin,combined with the actual situation of our hospital,the data form was designed to collect the information of vancomycin use in discharged medical records during Jan. 1th-Jun. 30 th,2013,and the utilization of vancomycin in our hospital was evaluated and analyzed retrospectively. RESULTS：During the utilization of vancomycin in our hospital,the qualified rates of temperature monitoring before and after treatment,white blood cell count and bacterial culture within 48 hours after first application were 100%;there were also some unreasonable use of vancomycin such as medication indications,usage and dosage,medication course and drug interaction,among which the qualified rate of the medication indications were 63.33%,that of usage and dosage 51.67%,medication course 51.67%,and drug interaction 61.67%. CONCLUSIONS：Problems or defects can be found in the clinical medication by DUE of vancomycin in our hospital,which is of great significance to the promotion of reasonable use of vancomycin.