| 离体心脏灌注模型的制备 |
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| 引用本文： | 李寒,徐序洁,张载高,贝亚军,解水本. 离体心脏灌注模型的制备[J]. 海军总医院学报, 2006, 19(3): 133-135 |
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| 作者姓名： | 李寒 徐序洁 张载高 贝亚军 解水本 |
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| 作者单位： | 海军总医院心外科,北京,100037 |
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| 摘 要： | 目的 通过制备大鼠离体心脏灌注模型,探讨模型制备的方法及注意事项.方法 健康成年大鼠20只,雌雄不限,取离体心脏,制备Langendorff模型及离体工作心脏灌注模型.结果 实验中成功18例(成功率90%).心脏均能持续稳定搏动,心脏收缩有力,左室内压为7.1～10.5 kPa,处于生理范围(6.3～10.3 kPa),心率250～300 /min,心律齐,心脏可平稳跳动6 h以上.结论 Langendorff模型及离体工作心脏灌注模型操作方便、稳定,是比较符合生理特性的离体心脏灌注模型.
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| 关 键 词： | 离体心脏 灌注模型制备 |
| 文章编号： | 1009-3427（2006）03-0133-03 |
| 收稿时间： | 2005-12-26 |
| 修稿时间： | 2005-12-26 |
Establishment of Isolated Rat Heart Model |
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| LI Han,XU Xu-jie,ZHANG Zai-gao,BEI Ya-jun,XE Shui-ben. Establishment of Isolated Rat Heart Model[J]. Journal of Naval General Hospital of PLA, 2006, 19(3): 133-135 |
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| Authors: | LI Han XU Xu-jie ZHANG Zai-gao BEI Ya-jun XE Shui-ben |
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| Affiliation: | Department of Cardiovascular Surgery, Naval General Hospital,Beijing 100037,China |
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| Abstract: | Objective To establish isolated rat heart model.Methods Twenty SD rats were divided into 5 groups randomly,isolated rat heart Langendorff model and isolated working heart model were established. Results Eighteen models were established successfully(90%).The pressure in left ventricle was 7.1-10.5 kPa,and the hearts could beat stably for more than 6 h.Conclusion In this study,we established isolated rat heart Langendorff model and isolated working heart model,which were very convenient and stable. |
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| Keywords: | Isolated rat heart Perfusion model preparation |
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