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鸦胆子油乳剂联合顺铂治疗肺癌胸水70例
引用本文:王红梅,廖国清,刘鹏辉,曲怡梅,解国清,刘士欣.鸦胆子油乳剂联合顺铂治疗肺癌胸水70例[J].中国肿瘤,2007,16(12):1035-1036.
作者姓名:王红梅  廖国清  刘鹏辉  曲怡梅  解国清  刘士欣
作者单位:解放军总医院第二附属医院,北京,100091
摘    要:对70例肺癌所致恶性胸腔积液患者随机分成联合组、化疗组,每组35例,均采用胸腔放置引流管放净胸水。联合组胸腔内每次注入鸦胆子油乳剂80 ̄100ml,顺铂20 ̄30mg/m2,化疗组胸腔内注入顺铂20 ̄30mg/m2,5 ̄7天1次,最多4次为1个疗程,1个月后观察疗效和毒副反应。联合组较化疗组近期疗效、生活质量明显提高(P<0.05),联合组毒副反应较化疗组低。

关 键 词:肺肿瘤  胸腔积液  鸦胆子油乳剂  顺铂
文章编号:1004-0242(2007)12-1035-02
收稿时间:2007-06-15
修稿时间:2007-09-07

Brucea Javanica Oil Emulsion Combined with Cisplatin Treatment for 70 Patients with Malignant Pleural Effusion of Lung Cancer
WANG Hong-mei, LIAO Guo-qing, LIU Peng-hui,et al..Brucea Javanica Oil Emulsion Combined with Cisplatin Treatment for 70 Patients with Malignant Pleural Effusion of Lung Cancer[J].Bulletin of Chinese Cancer,2007,16(12):1035-1036.
Authors:WANG Hong-mei  LIAO Guo-qing  LIU Peng-hui  
Institution:WANG Hong-mei, LIAO Guo-qing, LIU Peng-hui, et al.
Abstract:Seventy cases with pleural effusion of lung cancer were randomly divided into two groups: combined group (35 cases) and chemotherapy group (35 cases). All cases were drained pleural effusion by tube in thorax: brucea javanica oil emulsion (80~100ml) and cisplatin (20~30mg/m2) in combined group, cisplatin (20~30mg/m2) in chemotherapy group, once every 5~7 days (4 times for a course of treatment). The effect and toxicity were observed after one month. The short-term effect and quality of life in combined group were superior to in chemotherapy group (P<0.05) and combined group had less toxicity than chemotherapy group.
Keywords:lung neoplasms  pleural effusion  brucea javanica oil emulsion  cisplatin
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