不孕症相关因素及病因分析

目的:探讨与不孕症相关的因素及病因状况。方法:收集4 234对门诊初诊不孕患者年龄、月经和生育史、以及与不孕相关的检查资料进行分析。结果:男、女性不孕患者平均年龄分别为32.1岁和29.6岁，女性高龄不孕患者占13.9%；原发不孕占60.3%，继发不孕39.7%，女方因素与男方因素或双方因素导致的原发或继发不孕构成比有明显差异（P<0.01）；主要病因所占比重：女性输卵管、盆腔病变46%，其次为男性无精子症或少弱精子症36.4%，女性排卵异常10.2%。其中994对(23.5%)存在双方因素不孕。结论:加强女性输卵管、盆腔疾病的预防和男性生精功能障碍的机制研究可能对防治不孕症起重要作用。

Analysis on causes of infertility

Objective To investigate the situation of factors associated with infertility.Methods We investigated the age,menstrual cycle and family planning,family history,infertility diagnosis of 4 234 couples.Results The mean age of men patients and women was 32.1 and 29.6 years respectively.The rate of advanced women was 13.9%.Primary and secondery infertility was 60.3% and 39.7%,respectively,and with significant difference between female factors and male factors or both female and male factors(P<0.01).The main causes of infertility included: 46% with tubal defect and pelvic disease,36.4% suffered disorders of sperm production,15.9% with anovulation.There were 994 couples that both partners caused infertility,and constituted 23.5% among 4234 couples.Conclusion It may play an importance role to prevent infertility through strengthening the prevention of fallopian tube and pelvic disease,and researching on spermatogenesis.