Epithelioid sarcoma. Flow cytometric study of DNA content and regional DNA heterogeneity. |
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| Authors: | A K el-Naggar G M Garcia |
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| Affiliation: | Department of Pathology, University of Texas M.D. Anderson Cancer Center, Houston 77030. |
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| Abstract: | The DNA content and regional DNA heterogeneity in correlation with clinicopathologic parameters and patient survival were investigated in epithelioid sarcoma. Such neoplasms preponderantly manifest diploid DNA content and a remarkably stable intratumoral and intertumoral DNA content. Small tumor size (less than 5.0 cm) and low S-phase fraction (less than 5%) were significant prognostic factors in this study. Ploidy status, mitotic rate, age, and postsurgical treatment were not significantly correlated with survival. |
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