64层螺旋CT腹部扫描参数优化的初步研究

目的 利用测量模型探讨64层螺旋CT腹部扫描合理的管电流值.方法 (1)模型研究:设置管电压为120 kVp,管电流分别为450、400、380、360、340、320、300、280 mA,扫描测量模型中的CTP515低对比分辨率模块,3名阅片者独立评价图像质量,获得最优管电流条件及导致图像质量发生质变的管电流区间值后应用于临床研究.(2)临床研究:选取3个月内行2次腹部CT平扫检查患者45例.首次检查均采用管电流450 mA,第2次检查采用完全随机化分组方法把受检者分为3组,每组各15例,管电流设置组l使用最优管电流,组2使用最优管电流+区间值,组3使用最优管电流-区间值,3名阅片者对肝门、胰腺、肾上极3个层面进行诊断接受率评价,对腹主动脉、门静脉、肝脏、脾脏、胆囊、胰腺、肾皮质、肾髓质进行图像主观噪声评价.图像质量比较采用秩和检验,各组间受检者个体化因素比较采用方差分析.结果 (1)腹部CT扫描最优扫描管电流为340 mA,导致图像质量发生质变的区间值为40 mA.(2)对腹主动脉、门静脉主干、肝脏、脾脏、胰腺、胆囊、肾皮质、肾髓质及肝门、胰腺、肾上极3个层面的图像质量评分,组1内(340 mA和450 mA)和组2内(380 mA和450 mA)比较差异均无统计学意义(P值均＞0.05);组3内300 mA的评分为(2.92±0.62)、(2.92±0.62)、(2.64 ±0.84)、(2.72±0.82)、(2.63±0.71)、(2.51±0.84)、(3.04±0.72)、(3.04±0.72)、(2.63±0.71)、(2.52±0.73)、(2.93±0.81)分,450 mA的评分为(3.93±0.72)、(3.94±0.72)、(3.41±0.64)、(3.43±0.61)、(3.62±0.93)、(3.63 ±0.71)、(3.93±0.81)、(3.93±0.81)、(3.43±0.61)、(3.52±0.92)、(3.84±0.82)分,二者比较差异均有统计学意义(Z=-2.449～-2.236,P值均＜0.05).结论 降低管电流以降低腹部CT扫描辐射剂量的方案是可行和有效的,腹部CT扫描合理的管电流条件为340 mA.

Abstract：

Objective To investigate the appropriate low tube current of abdominal CT on a 64-slice spiral CT. Methods (1) Phantom study:The phantom Catphan500R was scanned with a fixed 120 kVp,and 450,400,380,360,340,320,300,280 mA, respectively. 15, 9, 8, 7, 6 mm diameter low-contrast objects with 1% contrast were scanned for evaluating image quality. CT images were graded in terms of lowcontrast conspicuity by using a five-point scale. Statistical analyses were performed to determine the appropriate tube current and the interval leading to the qualitative change. (2) Clinical study: 3 groups of 45 patients who had 2 examinations of non-enhanced abdominal CT within 3 months were enrolled. All patients were scanned with 450 mA at first scanning. For the second scanning, group-1 was scanned with optimal tube current, group-2 was scanned with optimal tube current plus interval, group-3 was scanned with optimal tube current sinus interval. CT images were graded in terms of the diagnostic acceptability at three anatomic levels including porta hepatis, pancreas and the upper pole kidney, and the image noises of eight organs including abdominal aorta, portal vein, liver, spleen, gallbladder, pancreas, renal cortex, renal medulla were graded by using a five-point scale. The image quality was compared with non-parametric rank sum test,and the individual factors of the patients were compared with the A VONA. Results (1) The optimal tube current and interval leading to the qualitative change were 340 mA and 40 mA respectively. (2) There were no significant differences in image quality between 340 mA and 450 mA in group-1, between 380 mA and 450 mA in group-2 (P ＞ 0. 05). There was significant difference in image quality between 300 mA and 450 mA in group-3 (the mean scores for 300 mA were 2. 92 ± 0. 62,2.92 ± 0. 62,2.64 ± 0. 84,2. 72 ±0.82,2.63 ±0.71,2.51 ±0.84,3.04 ±0.72,3.04 ±0.72,2.63 ±0.71,2.52 ±0.73,2.93 ±0.81respectively; for 450 mA were 3.93 ± 0. 72,3.94 ± 0. 72,3.41 ± 0. 64,3.43 ± 0. 61,3.62 ± 0. 93,3.63 ±0.71,3.93 ±0.81,3.93 ±0.81,3.43 ±0.61,3.52 ±0.92,3.84 ±0.82 respectively) (Z = -2.449 to - 2. 236, P ＜ 0. 05). Conclusion Radiation dose can be effectively reduced by using an appropriate and lower current of 340 mA.

Preliminary study of the optimization of abdominal CT scanning parameters on 64-slice spiral CT

Objective To investigate the appropriate low tube current of abdominal CT on a 64-slice spiral CT. Methods (1) Phantom study:The phantom Catphan500R was scanned with a fixed 120 kVp,and 450,400,380,360,340,320,300,280 mA, respectively. 15, 9, 8, 7, 6 mm diameter low-contrast objects with 1% contrast were scanned for evaluating image quality. CT images were graded in terms of lowcontrast conspicuity by using a five-point scale. Statistical analyses were performed to determine the appropriate tube current and the interval leading to the qualitative change. (2) Clinical study: 3 groups of 45 patients who had 2 examinations of non-enhanced abdominal CT within 3 months were enrolled. All patients were scanned with 450 mA at first scanning. For the second scanning, group-1 was scanned with optimal tube current, group-2 was scanned with optimal tube current plus interval, group-3 was scanned with optimal tube current sinus interval. CT images were graded in terms of the diagnostic acceptability at three anatomic levels including porta hepatis, pancreas and the upper pole kidney, and the image noises of eight organs including abdominal aorta, portal vein, liver, spleen, gallbladder, pancreas, renal cortex, renal medulla were graded by using a five-point scale. The image quality was compared with non-parametric rank sum test,and the individual factors of the patients were compared with the A VONA. Results (1) The optimal tube current and interval leading to the qualitative change were 340 mA and 40 mA respectively. (2) There were no significant differences in image quality between 340 mA and 450 mA in group-1, between 380 mA and 450 mA in group-2 (P ＞ 0. 05). There was significant difference in image quality between 300 mA and 450 mA in group-3 (the mean scores for 300 mA were 2. 92 ± 0. 62,2.92 ± 0. 62,2.64 ± 0. 84,2. 72 ±0.82,2.63 ±0.71,2.51 ±0.84,3.04 ±0.72,3.04 ±0.72,2.63 ±0.71,2.52 ±0.73,2.93 ±0.81respectively; for 450 mA were 3.93 ± 0. 72,3.94 ± 0. 72,3.41 ± 0. 64,3.43 ± 0. 61,3.62 ± 0. 93,3.63 ±0.71,3.93 ±0.81,3.93 ±0.81,3.43 ±0.61,3.52 ±0.92,3.84 ±0.82 respectively) (Z = -2.449 to - 2. 236, P ＜ 0. 05). Conclusion Radiation dose can be effectively reduced by using an appropriate and lower current of 340 mA.