| 毛鸡骨草醇提液对HepG2.2.15细胞乙型肝炎表面 抗原及乙型肝炎E抗原的影响 |
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| 引用本文： | 陈晓白,王晓平,韦敏. 毛鸡骨草醇提液对HepG2.2.15细胞乙型肝炎表面 抗原及乙型肝炎E抗原的影响[J]. 中国实验方剂学杂志, 2011, 17(22): 184-186 |
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| 作者姓名： | 陈晓白 王晓平 韦敏 |
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| 作者单位： | 1. 玉林师范学院,广西玉林,537000
2. 广西玉林市卫生学校,广西玉林,537000 |
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| 基金项目： | 广西教育厅科研资助项目(200710MS052);广西玉林市科技局项目(玉市科攻0881038) |
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| 摘 要： | 目的:观察毛鸡骨草体外抗乙型肝炎病毒(HBV)的作用。方法:采用MTT法检测毛鸡骨草对HepG2.2.15细胞的半数毒性浓度(TC50)和最大无毒浓度(TC0),采用酶联免疫吸附实验(ELISA)法测定
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| 关 键 词： | 毛鸡骨草 HepG2.2.15细胞 乙型肝炎表面抗原 乙型肝炎E抗原 |
| 收稿时间： | 2011-07-12 |
Effect of Abrus mollis Hance on HBsAg and HBeAg in the HepG2.2.15 Cells |
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| CHEN Xiao-bai,WANG Xiao-ping and WEI Min. Effect of Abrus mollis Hance on HBsAg and HBeAg in the HepG2.2.15 Cells[J]. China Journal of Experimental Traditional Medical Formulae, 2011, 17(22): 184-186 |
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| Authors: | CHEN Xiao-bai WANG Xiao-ping WEI Min |
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| Affiliation: | Yulin Teachers College, Yulin 537000, China;Yulin Teachers College, Yulin 537000, China;Guangxi Yulin Health School, Yulin 537000, China |
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| Abstract: | Objective: To observe the inhibitive effect of Abrus mollis Hance on HBV. Method: The TC50 and TC0 of A. mollis to the HepG2.2.15 ceils were determined by MTT assay. The effect of 0 five different concentrations of alcohol extract of A. mollis on HBsAg and HBeAg in the HepG2.2.15 cells was determined by ELISA. Result: A. mollis had a inhibiting effect on the HBsAg and HBeAg with maximum inhibition ratio adding up to 33.1% and 40.1%,respectively, in which the affective time was 144 h and the density was 4 g·L-1. Conclusion: A. mollis can significantly inhibit HBV in vitro. |
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| Keywords: | Abrus mollis HepG 2.2.15 cell HBsAg HBeAg |
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