滋阴降火方治疗绝经综合征阴虚火旺证

目的:观察中医滋阴降火方对绝经综合征阴虚火旺证女性患者临床症状的改善作用,探讨其作用机制。方法:将符合绝经综合征阴虚火旺证诊断标准的患者随机分入治疗组和对照组,各30例,治疗组予滋阴降火方,对照组予安慰剂,4周为1个疗程,共3个疗程。观察两组用药前后主症潮热、出汗计分,Kupperman症状积分,阴虚火旺证症状积分变化。结果:治疗组治疗后主症潮热、出汗发作次数及程度均下降,有统计学意义(P<0.05);对照组变化无统计学意义;治疗组与对照组治疗后Kupperman症状及阴虚火旺症状积分均下降,但治疗组对总体症状的改善显著优于对照组(P<0.01)。结论:滋阴降火方能缓解阴虚火旺型绝经综合征患者的临床综合症状,对主症潮热、出汗的缓解作用尤为明显,能够提高患者的生活质量。

Clinical Observation on Ziyin Jianghuo Fang for the Treatment of 60 Patients with Menopausal Syndrom Caused by Deficiency of Yin and Exess of Fire

Objective: To observe the therapeutic effect of Ziyin Jianghuo Fang(ZYJHF) on patients suffering from menopausal syndrom (MPS) caused by deficiency of yin and exess of fire,try to explore its potential mechanism. Method: Sixty cases with MPS caused by deficiency of yin and exess of fire were randomly divided into two groups. The therapy group(30) was treated by ZYJHF, the control group(30) was treated by placebo A course lasted for 4 weeks, and total treatment was 3 courses. Result: The main symptom:flush, sweating in the therapy group was relieved(P<0.05),while in the control group the symptom was not relieved. In the two groups, the Kupperman scores of and traditional Chinese medicine(TCM) symptom were decreased significantly(P<0.05), but with significant difference in the two groups(P<0.01). Conclusion: ZYJHF could relief the clinical symptoms of MPS, particularly effective on hectic fever and perspiration, it can improve the life quality of patients suffering from MPS caused by deficiency of yin and exess of fire.