| 糖脉康颗粒清除DPPH自由基的作用 |
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| 引用本文： | 赵启鹏,兰莎,张艺. 糖脉康颗粒清除DPPH自由基的作用[J]. 中国实验方剂学杂志, 2011, 17(21): 41-45 |
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| 作者姓名： | 赵启鹏 兰莎 张艺 |
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| 作者单位： | 1. 宁夏回药现代化工程技术研究中心,银川 750004;宁夏医科大学药学院,银川 750004
2. 成都中医药大学民族医药学院,成都,611137 |
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| 基金项目： | 国家"十一五"科技支撑计划项目(2007BAI40B03) |
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| 摘 要： | 目的:建立体外清除DPPH方法,评价糖脉康颗粒体外抗氧化作用。方法:对清除DPPH方法进行反应时间,反应温度,DPPH的浓度与吸光度的关系,糖脉康的提取溶剂,提取方法等考察,对14批糖脉康及含药血清进行体外清除DPPH实验。结果:糖脉康以60%甲醇为溶剂,超声提取30 min,与0.099 8 g.L-1的DPPH于60℃反应50 min;14批糖脉康颗粒对DPPH的平均IC50=0.48 mg(生药量);含药血清对DPPH清除率与空白血清比有所下降。结论:糖脉康颗粒具有体外抗氧化作用。
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| 关 键 词： | 糖脉康颗粒 DPPH法 抗氧化 |
| 收稿时间： | 2011-05-29 |
DPPH Radical Scavenging Effect of Compound Tangmaikang |
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| ZHAO Qi-peng,LAN Sha and ZHANG Yi. DPPH Radical Scavenging Effect of Compound Tangmaikang[J]. China Journal of Experimental Traditional Medical Formulae, 2011, 17(21): 41-45 |
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| Authors: | ZHAO Qi-peng LAN Sha ZHANG Yi |
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| Affiliation: | Ningxia Research Center of Modern Hui Medicine Engineering and Technology, Yinchuan 750004, China; College of Pharmacy, Ningxia Medical University, Yinchuan 750004, China;College of Ethnomedicine, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China;College of Ethnomedicine, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China |
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| Abstract: | Objective:To establish a method of scavenging DPPH radical,and then evaluate DPPH radical scavenging effect of compound Tangmaikang.Method: Investigated the reaction time,temperature,the concentration of DPPH and the extraction solvent and method,the study on the DPPH radical scavenging effect of 14 batches Tangmaikang and drug-containing serum was carried out.Result: Tangmaikang was extracted with 60% methanol by ultrasonic for 30 min.The optimum reaction conditions were obtained as follows:DPPH concentrat... |
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| Keywords: | Tangmaikang DPPH antioxidant |
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