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瑞香狼毒提取物尼地吗啉的抗肿瘤研究概况
引用本文:王园园,王鑫,王义善. 瑞香狼毒提取物尼地吗啉的抗肿瘤研究概况[J]. 药学实践杂志, 2011, 29(5): 328-330,335
作者姓名:王园园  王鑫  王义善
作者单位:解放军第107医院国家中西医结合肿瘤治疗重点专科,山东烟台,264002
基金项目:全军科技攻关项目(06G034).
摘    要:本文就瑞香狼毒中抗肿瘤活性成分尼地吗啉的抗肿瘤机制、研究现状及其临床应用存在的问题进行了较完整的总结和介绍,进一步分析了尼地吗啉作为一种抗癌药物的可行性及临床应用减毒增效方案,籍此为尽可能的发挥祖国传统肿瘤中医中药巨大潜能,深入研究抗肿瘤有效单体成分提供参考。

关 键 词:瑞香狼毒  尼地吗啉  中药单体  抗肿瘤
收稿时间:2010-11-05
修稿时间:2011-04-29

Progress on diterpenoids gnidimacrin in Stellera chamaejasma L.
WANG Yuan-yuan,WANG Xin and WANG Yi-shan. Progress on diterpenoids gnidimacrin in Stellera chamaejasma L.[J]. The Journal of Pharmaceutical Practice, 2011, 29(5): 328-330,335
Authors:WANG Yuan-yuan  WANG Xin  WANG Yi-shan
Affiliation:The Center for Tumor Treatment, 107th Hospital of PLA, Yantai 264002, China;The Center for Tumor Treatment, 107th Hospital of PLA, Yantai 264002, China;The Center for Tumor Treatment, 107th Hospital of PLA, Yantai 264002, China
Abstract:A relatively complete summary on the anti-tumor component gnidimacrin was introduced, which was extracted from Stellera chamaejasma L. The research status of gnidimacrin's antitumor mechanism and its clinical application were reviewed. A further analysis on the feasibility and attenuated efficiency programs of the Gnidimacrin as an antitumor drug was made. The review could provide reference to exert the enormous potential of Chinese traditional medicine as much as possible and to deeply excavate the effective monomers.
Keywords:Stellera chamaejasma L.  gnidimacrin  chinese medicine  antitumor
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