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我院107例药品不良反应报告分析
引用本文:吴婷婷,田硕,左艳敏,郭婧. 我院107例药品不良反应报告分析[J]. 药学实践杂志, 2011, 29(5): 394-395,397
作者姓名:吴婷婷  田硕  左艳敏  郭婧
作者单位:1. 北京军区总医院263临床部药械科,北京,101149
2. 北京军区总医院263临床部儿科,北京,101149
摘    要:目的了解我院药品不良反应(ADR)发生的特点及规律。方法对我院2009年4月至2010年5月收集的107例ADR报告,按患者性别、年龄、给药途径、药物剂型、药品种类、ADR累及器官或系统及临床表现等进行分类统计与分析。结果 107例报告中,涉及药品69种;以抗感染药居多,占48.62%;静脉给药方式是引发ADR的重要给药途径,占81.31%;ADR最常见的临床表现为皮肤及其附件损害,占35.53%。结论临床应进行必要的用药干预和指导,加强ADR监测,以减少ADR的发生率。

关 键 词:药品不良反应  报告  分析
收稿时间:2011-03-10
修稿时间:2011-05-30

Analysis of 107 cases of drug adverse reaction report in our hospital
WU Ting-ting,TIAN Shuo,ZUO Yan-min and GUO Jing. Analysis of 107 cases of drug adverse reaction report in our hospital[J]. The Journal of Pharmaceutical Practice, 2011, 29(5): 394-395,397
Authors:WU Ting-ting  TIAN Shuo  ZUO Yan-min  GUO Jing
Affiliation:Department of Pharmacy, No. 263 Hospital of PLA, Beiiing, 101149 China;Department of Pharmacy, No. 263 Hospital of PLA, Beiiing, 101149 China;Department of Pharmacy, No. 263 Hospital of PLA, Beiiing, 101149 China;Department of Pediatrics, No. 263 Hospital of PLA, Beijing 101149 China
Abstract:Objective To investigate the characteristics and general pattern of drug adverse reactions (ADR)occurred in our hospital. Methods A total of 107 ADR cases reported in our hospital from Apr.2009 to Mar.2010 were analyzed statistically in respect of patients' age and sex, route of administration, dosage form, category of drug, organs and systems involved in ADR and clinical manifestions etc. Results 69 kind of drug were involved in 107 ADR cases, 48.6% were induced by anti-infective drugs, 81.31% were induced by means of intravenous route, and 35.53% manifested as lesions of skin and its appendants. Conclusion It was necessary to intervene and guide clinical use of drug, strengthen monitoring of ADR and reduce occurrences of ADR.
Keywords:adverse drug reactions (ADR)  reports  analysis
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