| 多指标正交试验法优选坎离颗粒提取工艺 |
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| 引用本文： | 文小燕,刘力,徐德生.多指标正交试验法优选坎离颗粒提取工艺[J].中国实验方剂学杂志,2011,17(17):20-22. |
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| 作者姓名： | 文小燕 刘力 徐德生 |
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| 作者单位： | 上海中医药大学附属曙光医院,上海,200021 |
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| 基金项目： | 上海市科委中药现代化专项基金项目(08DZ1972200) |
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| 摘 要： | 目的:优选坎离颗粒的提取工艺条件。方法:采用正交设计试验法,以提取液中黄芪甲苷、芍药苷、总皂苷和总生物碱含量为综合评分指标,多指标成分优选坎离颗粒提取工艺。结果:优选的工艺条件为坎离颗粒处方量加水10倍,提取3次,每次45 min,提取前浸泡45 min。结论:该提取工艺条件稳定,重现性好。
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| 关 键 词： | 坎离颗粒 提取工艺 正交实验 多指标成分 综合评价 |
| 收稿时间： | 5/3/2011 12:00:00 AM |
Optimization Study on Extraction Technology of Kanli Granules by Orthogonal Design with Multi-target |
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| WEN Xiao-yan,LIU Li and XU De-sheng.Optimization Study on Extraction Technology of Kanli Granules by Orthogonal Design with Multi-target[J].China Journal of Experimental Traditional Medical Formulae,2011,17(17):20-22. |
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| Authors: | WEN Xiao-yan LIU Li and XU De-sheng |
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| Institution: | Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200021, China;Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200021, China;Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200021, China |
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| Abstract: | Objective: To optimize the extracting technology conditions of Kanli Granules. Method: Orthogonal design was used to optimize the extraction conditions, with the content of multi-target ingredients such as astragaloside, paeoniflorin, total saponins and total alkaloids as comprehensive evaluation indexes. Result: The optimum extraction conditions were as follows: extracted 3 times with 10 fold water,45 minutes each time. Conclusion: The optimum extraction conditions was stable and reproducible. |
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| Keywords: | Kanli granules extraction technology orthogonal design multi-targets ingredients comprehensive evaluation |
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