多指标综合评分法考察金银花连翘药对最佳提取工艺

目的:确定金银花连翘药对的最佳提取工艺。方法:以绿原酸、木犀草苷、槲皮素和连翘脂素为考察指标,采用综合评分法,对采用乙醇回流的提取时间、提取次数、溶剂浓度和用量进行考察。结果:金银花连翘药对的最佳提取工艺为8倍量60%乙醇提取3次,每次提取2 h。结论:本结果可为金银花连翘药对的提取工艺研究提供参考。

Investigate Optimum Extraction Technology of Drug Couple Composed of Lonicerae Japonicae Flos and Forsythiae Fructus by Multi-index Comprehensive Evaluation Method

Objective: To obtain optimum extraction process of drug couple composed of Lonicerae Japonicae Flos and Forsythiae Fructus. Method: Examined extraction time,extraction times,concentration and the amount of ethanol with chlorogenic acid, luteolin, quercetin and forsythiaside as indexes by multi-index comprehensive evaluation method. Result: Optimal extraction technology of the drug couple was as followed: extracted 3 times with 8 times amount of 60% ethanol for 2 h each time. Conclusion: The optimum extraction technology could provide a reference to study on the extraction technology of drug couple composed of Lononicerae Japonicae Flos and Forsythiae Fructus.