| 知母皂苷及其苷元的药理作用研究进展 |
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| 引用本文： | 蔡飞,王维泓,高守红,陈万生.知母皂苷及其苷元的药理作用研究进展[J].药学实践杂志,2011,29(5):331-335. |
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| 作者姓名： | 蔡飞 王维泓 高守红 陈万生 |
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| 作者单位： | 1. 解放军广州军区机关门诊部药械科,广东广州,510080
2. 第二军医大学附属长征医院药学部,上海,200003 |
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| 摘 要： | 知母皂苷及其苷元是临床常用中药材知母的最主要活性成分，具有广泛的生物活性和药理作用。研究表明，知母皂苷及其苷元具有防治老年痴呆症、保护脑缺血损伤、抗凝血、抗氧化、抗肿瘤、抗骨质疏松、抗炎、降血压、降血糖及降血脂等药理活性。本文对知母皂苷及其苷元的上述药理作用研究进展进行综述，为进一步开发利用提供参考。
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| 关 键 词： | 知母皂苷 药理作用 研究进展 |
| 收稿时间： | 2011/4/12 0:00:00 |
| 修稿时间： | 2011/7/13 0:00:00 |
Advances in the pharmacological studies on timosaponins and their sapogenins |
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| CAI Fei,WANG Wei-hong,GAO Shou-hong and CHEN Wan-sheng.Advances in the pharmacological studies on timosaponins and their sapogenins[J].The Journal of Pharmaceutical Practice,2011,29(5):331-335. |
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| Authors: | CAI Fei WANG Wei-hong GAO Shou-hong and CHEN Wan-sheng |
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| Institution: | Department of pharmacy, Command outpatient department, Guangzhou Military District of PLA, Guangzhou 510080, China;Department of pharmacy, Command outpatient department, Guangzhou Military District of PLA, Guangzhou 510080, China;Department of pharmacy, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China;Department of pharmacy, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China |
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| Abstract: | Timosaponins and their sapogenins were the major active components from a commonly used Chinese herbal medicine, Anemarrhenae Rhizoma. Studies showed that they had a broad range of pharmacological effects such as improving senile dementia, preventing cerebral ischemia, anti-coagulated blood, anti-oxidant, anti-tumor, anti-osteoporosis, anti-inflammation, lowering blood pressure, lowering blood sugar and lowering blood fat. Recent advances in the above biological activities were reviewed in this paper. |
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| Keywords: | timosaponin pharmacological effects advance |
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