| 内生场腹腔热灌注化疗对恶性腹盆腔肿瘤患者T细胞亚群的影响 |
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| 引用本文： | 周淑云,关铁,邹庆华. 内生场腹腔热灌注化疗对恶性腹盆腔肿瘤患者T细胞亚群的影响[J]. 实用口腔医学杂志, 2010, 39(7): 589-590 |
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| 作者姓名： | 周淑云 关铁 邹庆华 |
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| 作者单位： | 中国石油天然气集团公司中心医院,065000 |
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| 摘 要： | 目的探讨内生场腹腔热灌注化疗(IPHC)对恶性腹盆腔肿瘤患者T细胞亚群的影响。方法对24例腹盆腔恶性肿瘤进行以顺铂为主的腹腔热灌注化疗,检测热灌注化疗前后T细胞亚群的表达,探讨热灌注化疗对细胞免疫的影响,统计学处理采用配对t检验。结果腹腔热灌注化疗后CD4、自然杀伤(NK)细胞数目及CD4/CD8比值明显提高。结论腹腔热灌注化疗可以提高CD4、NK细胞数目及CD4/CD8比值,增强机体的免疫机能,提高抗肿瘤效应。
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| 关 键 词： | T淋巴细胞亚群 肿瘤,各部位 灌注化疗 |
Influence of IPHC on T lymphocyte subset in abdomen-pelvic cavity cancer |
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| Abstract: | Objective To study the influence of IPHC on T lymphocyte subset in abdomen-pelvic cavity cancer.Methods Twenty four cases of abdomen-pelvic cavity cancer patients were treated by IPHC,and the T lymphocyte subset before and after treatment were analyzed with paired t test.Results The amount of CD4,NK and the radio of CD4/CD8 were elevated by IPHC.Conclusion IPHC can enhance the amount of CD4,NK and the radio of CD4/CD8,improve the patients' immune function and antitumor response. |
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| Keywords: | T-lymphocyte subsets Neoplasms by site Perfusion chemotherapy |
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