EUS diagnosis of cystic lesions of the pancreas |
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Authors: | Bounds B C Brugge W R |
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Institution: | (1) Massachusetts General Hospital, 55 Fruit Street, Blake 4 GI Unit, 02114 Boston, MA |
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Abstract: | Summary
Background. Cystic tumors of the pancreas are composed of benign, premalignant, malignant, and inflammatory lesions that are traditionally
difficult to diagnose. Most of the tumors are initially detected on CT/US scanning, but often the morphological characteristics
are insufficient for making a definitive diagnosis. Endoscopic ultrasound (EUS) may be an ideal tool for imaging of these
lesions because it can provide highly detailed imaging without interference by bowel or air. Furthermore, EUS can direct fine
needle aspiration of the lesions, providing cyst fluid for cytologic examination. The findings of cyst fluid cytology can
be complemented by the use of cyst fluid tumor makers such as CEA. Using the morphologic appearance by endosonography, the
results of cytology, and tumor marker analysis, EUS can often differentiate between benign, malignant, and inflammatory cystic
lesions of the pancreas. |
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Keywords: | |
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