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Genetics analysis of haptoglobin gene in Fujian Han nationality
Authors:Qilian ZOU  Xiangquan LIN  Yuanzhong CHEN  Ying LIN
Affiliation:(1) Division of Cell Biology and Genetics, Fujian Medical University, Fuzhou, 350004, China;(2) Fuzhou Children Hospital, Fuzhou, 350005, China;(3) Fujian Institute of Hematology, The Affiliated Union Hospital, Fujian Medical University, Fuzhou, 350001, China
Abstract:To study the genetic features (characteristics) of haptoglobin gene, four different age groups of Fujian Han people were investigated. The phenotypes of the haptoglobin of four different groups were analyzed by using polyacrylamide gel electrophoresis. The frequency of HP 1 in the population of Fujian Han nationality accounted for 0.340, among which children, youths, middle aged and elder groups were 0.307, 0.338, 0.363 and 0.383, respectively. The Hp0–0 phenotype frequency was 0.026 in which the four age groups accounted for 0.032, 0.046, 0.014 and 0.014, respectively. The frequency of Hp 1 gene is rising with increasing age. The frequency of Hp0–0 phenotype is highest in the middle aged group and then tends to drop with increasing age. __________ Translated from Journal of Fujian Medical University, 2007, 41(5): 452–453 [译自: 福建医科大学学报]
Keywords:Han nationality  Fujian  haptoglobin  genetics  gene  polyacrylamide gel electrophoresis
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