|
|||||
|
|
Treatment of spinocerebellar ataxia with buspirone |
|
| Authors: | Assadi Mitra Campellone Joseph V Janson Christopher G Veloski J Jon Schwartzman Robert J Leone Paola |
| Affiliation: | aDepartment of Medicine, Division of Neurology, Cooper University Hospital/Robert Wood Johnson Medical School, Camden, New Jersey, USA bDepartments of Neurology and Molecular Genetics, Cooper University Hospital/Robert Wood Johnson Medical School, Camden, New Jersey, USA cCenter for Research in Medical Education and Health Care, Jefferson Medical College of Thomas Jefferson University Philadelphia, Pennsylvania, USA dChairman, Department of Neurology; Drexel University Hospital, Philadelphia, Pennsylvania, USA |
| Abstract: | Preliminary data suggest potential benefit of 5-HT receptor agonists in the treatment of ataxias. We studied the effects of buspirone in a cohort of twenty patients with spinocerebellar ataxia (SCA). Twenty patients were treated in this double-blind, placebo controlled, cross-over trial with either buspirone HCl 30 mg twice daily or placebo for 3 months. Buspirone was not shown to be superior to placebo in the treatment of patients with SCA. |
| Keywords: | Ataxia SCA Buspirone |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ | |