Esophageal Small Cell Carcinoma with Ectopic Production of Parathyroid Hormone-Related Protein (PTHrp), Secretin, and Granulocyte Colony-Stimulating Factor (G-CSF) |
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Authors: | Ryuichi Nagashima Katsuhiro Mabe Tsuneo Takahashi |
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Affiliation: | Second Department of Internal Medicine, Yamagata University School of Medicine, Iida-Nishi, Japan. |
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Abstract: | A patient with primary small cell carcinoma of the esophagus is reported, in whom we have studied the secretion of a variety of hormones and cytokines. The tumor was an intermediate cell type of small cell carcinoma and had either epithelial and neuroendocrinological characteristics. Furthermore, hypercalcemia and neutrophilia were present, and the tumor was shown to produce PTHrp, secretin, and G-CSF. The present case is the first report of primary small cell carcinoma of the esophagus with ectopic production of PTHrp, secretin, and G-CSF. |
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Keywords: | SMALL CELL CARCINOMA ESOPHAGEAL NEOPLASM ECTOPIC HORMONE PRODUCTION PARATHYROID HORMONE RELATED PROTEINPTHRP SECRETIN GRANULOCYTE COLONY STIMULATING FACTORG-CSF |
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