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联合检测CEA、NSE和CYFRA21-1在肺癌诊断中的价值
引用本文:杜红心,罗海峰,彭必江,陈蓉,程钢,林岚.联合检测CEA、NSE和CYFRA21-1在肺癌诊断中的价值[J].国际检验医学杂志,2010,31(5):447-448.
作者姓名:杜红心  罗海峰  彭必江  陈蓉  程钢  林岚
作者单位:重庆三峡中心医院生化科,404000
摘    要:目的探讨肿瘤标志物CEA、NSE和CYFRA21-1联合检测对肺癌的诊断价值。方法检测不同病理类型肺癌患者的血清中CEA、NSE和CYFRA21-1水平。结果肺癌组血清CEA、NSE和CYFRA21-1水平明显高于肺良性疾病患者(P0.05);CEA+NSE+CYFRA21-1诊断灵敏度明显高于单项肿瘤标志物(P0.05)。结论血清CEA、NSE和CYFRA21-1联合检测有助于肺癌临床诊断。

关 键 词:肺肿瘤  生物学标记  实验室技术和方法

Clinical significance of Joint measuring CYFRA21-1, CA153 and NSE for lung cancer
Abstract:Objective To investigate the diagnostic value of Joint determination of CEA,NSE and CYFRA21-1 in serum from patients with lung cancer.Methods Detected the CEA、NSE、CYFRA21-1 in different type patients with lung cancer.Results In lung cancer group,the levels of CEA,NSE and CYFRA21-1 were significantly higher than those group of benign lung disease (P<0.05).The sensitivity of joint measurement CEA,NSE and CYFRA21-1 was significantly higher than that of each tumor marker(P<0.05).Conclusion Joint measurement of CEA,NSE and CYFRA21-1 is helpful to diagnosis of lung cancer.
Keywords:Lung Neoplasms  Biological Markers  Laboratory Techniques and Procedures
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