呼吸系统疾病中中医辨证与真菌感染的相关性研究

目的：探讨真菌感染呼吸系统疾病的中医辨证特点，分析中医辨证分型与真菌感染的相关性，为中西医结合辨证和治疗提供理论依据。方法：按中医辨证理论，将275例呼吸系统疾病辨证分为4型，即外寒内饮型70例、肺热壅盛型67例、痰湿内盛型73例、脾肾阳虚型65例。并对患者的痰液标本进行真菌培养，利用美国Micro Scan自动细菌生长系统进行细菌鉴定，分析呼吸系统疾病中医辨证不同分型真菌感染的特点和规律。结果：在275例呼吸系统疾病中真菌感染率为25．5％。在中医辨证不同分型中，真菌感染率外寒内饮型为1.4％、肺热壅盛型为19．4％、痰湿内盛型为63．0％、脾肾阳虚型为15．3％。结论：呼吸系统疾病中医辨证不同分型与真菌感染密切相关，痰湿内盛型真菌感染率最高，外寒内饮型感染率最低，以白色念珠菌感染为主。

Correlation Research between Syndromes of Chinese Medicine and Fungous Infection on Respiratory System Disease

Objectives： discover syndrome differentiated characteristics of fungus infection of respiratory System Disease （RSD）, analyze correlation between Chinese medicine syndromes and fungus infection, and provide theoretical basis for integrative Chinese and western medical treatment. Methods：according to syndrome differentiation theory,275 cases of RSD were categorized as External Cold and Internal Fluid Retention （ ECIFR, 70 cases）, Lung Heat Congestion （ LHC, 67 cases）, Exuberant Internal Phlegm Dampness （ EIPD,73 cases）, Yang Deficiency Of Spleen and Kidney（ YDSK,65 cases）. Mycetes was cultivated in the phlegm samples and identified by US Micro Scan Automated Microbic System. Analysis on characteristics and mechanism of fungous infection was made to each syndrome category. Results： of 275 RSD cases ,the total infection rate was 25.5% ; that of ECIFR was 1.4%, LHC, 19.4% ; EIPD,63.0% ; YDSK, 15. 3%. Conclusion：RSD categorized in syndrome of Chinese medicine were closely correlated to fungus infection. Infection rate was the highest in the syndrome of Exuberant Internal Phlegm Dampness, and the lowest in the pattern of External Cold and Internal Fluid Retention. The majority of fungus infected is Blastomyces albicans.