三组新生儿的诱发性耳声发射的检测分析

目的　研究新生儿的畸变产物耳声发射 (DPOAE)和瞬态诱发耳声发射 (TEOAE)的特点 ,评价其在新生儿听力筛选中的作用。方法　应用Capella耳声发射分析仪对正常新生儿组、剖腹产儿组、新生儿监护病房组三组新生儿进行DPOAE、TEOAE检测。结果　得出正常新生儿的诱发性耳声发射 (EOAE)的正常参考值和正常新生儿的DPOAE图 ;三组新生儿EOAE筛查的通过率分别为 96.1% (12 3 / 12 8)、90 .8% (10 9/ 12 0 )、81.6% (93 /114 ) ,其中新生儿监护病房组的通过率与前两组比较有统计学意义 (P <0 .0 1) ;各组间DPOAE与TEOAE的筛查通过率差异均有统计学意义 (P <0 .0 1) ;正常新生儿与剖腹产儿的DPOAE的幅值和信噪比差异无统计学意义(P >0 .0 5)。结论　在病房内 (非隔音 )进行听力筛选时 ,可明显降低假阳性率 ;剖腹产因素对新生儿耳声发射未见影响 ;对高危新生儿进行听力筛选更有意义

Measurement and analysis of EOAE in three groups of neonates

ObjectiveTo study the properties of dis torion product otoacaustic emission(DPOAE) and transient evoked otoacaustic emission (TEOAE) in neonates, and evaluate the application of evoked otoacaustic emission (EOAE) in neonatal hearing screening. MethodsDPOAE and TEOAE were separately measured in three groups of neonates: normal neonates (NN), Cassarean section neonates (CSN) and neonatal intensive care unit neonates(NICUN) with Capella emission analyzer. ResultsDP-gram graph and normal referral value of EOAE in NN were obtained. The pass-rates were 96.1% (123/128), 90.8% (109/120) and 81.6% (93/114) in NN, CSN, NICUN respectivly, but the pass-rate in NICUN was lower than those in NN and in CSN (P< 0.01 ). The screening pass-rate appeared significantly different between DPOAE and TEOAE in all groups (P< 0.01 ). The amplitude and S/N-ratio had no significant difference between NN and CSN. ConclusionDPOAE can obviously reduce false positive rate in hearing screening, specially in none sound-treated environment; The effect of CSN factors upon EOAE isn't found in neonates. Hearing screening in NICUN (high-risk neonates) is of much more significance.