Institution: | a Queensland Radium Institute Laboratory, Queensland Institute of Medical Research, Bancroft Centre, Brisbane, 4029, Queensland, Australia b St. George Cancer Care Centre, St. George Hospital, Kogarah, 2217, N.S.W., Australia |
Abstract: |
: Merkel cell carcinoma (MCC), being a small cell carcinoma, would be expected to be sensitive to radiation. Clinical analysis of patients at our center, especially those with macroscopic disease, would suggest the response is quite variable. We have recently established a number of MCC cell lines from patients prior to radiotherapy, and for the first time are in a position to determine their sensitivity under controlled conditions. |